A condition where abnormal proteins (amyloid) accumulate in organs and tissues, impairing their function.¹

Also referred to as transthyretin amyloid cardiomyopathy. A rare, progressive heart condition caused by by toxic amyloid buildup in the heart.^2–5

A disease of the heart muscle making it harder to pump blood effectively.⁶

Imaging test providing detailed pictures of the heart and blood vessels.⁷

Ultrasound test showing heart structure and function.⁸

DNA test identifying inherited gene mutations that are associated with ATTR-CM.⁵

Condition where the heart cannot pump blood efficiently, causing shortness of breath and leg swelling.^9,10

Also called variant ATTR-CM. A genetic form of ATTR-CM inherited in families, more common in African American, Portuguese, and Irish populations.^2,3

Imaging scan that creates images of the body’s internal organs and tissues.¹¹

A non-invasive type of nuclear scintigraphy used to detect transthyretin amyloidosis.¹¹

A liver-produced protein that carries thyroid hormone and vitamin A. Misfolding and aggregation leads to amyloid deposits.¹²

A type of ATTR-CM not caused by inherited gene mutations; associated with aging.²