Medical Director

BridgeBio Oncology San Francisco, CA/Hybrid Clinical Development

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About BridgeBio Oncology Therapeutics & BridgeBio Pharma

BridgeBio Oncology Therapeutics (“BBOT”) is our team of researchers working to develop novel therapeutics to address dire unmet needs in oncology. Led by top scientists with extensive track records in drug development, like Frank McCormick and Eli Wallace, our team utilizes structure-based drug discovery techniques to target some of oncology’s most challenging and validated molecular targets, including KRAS and PI3Kα. We are focused and committed to patients, scientific excellence, and operational agility, and we understand that every minute counts in our efforts to develop new therapies to transform the lives of people living with cancer. Our main oncology laboratory is located in South San Francisco, though our research collaborators span the country and globe.

BridgeBio is a biopharmaceutical company founded to discover, create, test, and deliver transformative medicines to treat patients who suffer from genetic diseases and cancers with clear genetic drivers. We bridge the gap between remarkable advancements in genetic science in academic institutions and the delivery of meaningful medicines to patients. Founded in 2015, the company has built a portfolio of 30+ drug development programs ranging from preclinical to late-stage development in multiple therapeutic areas including genetic dermatology, precision oncology, cardiology, endocrinology, neurology, pulmonology, and renal disease, with two approved drugs.

Our focus on scientific excellence and rapid execution aim to translate today’s discoveries into tomorrow’s medicines. We have U.S. offices in San Francisco, Palo Alto, Boston, New York, and Raleigh, with small satellites in other parts of the country. We also have international offices in Montreal, Canada, and Zug, Switzerland, and are expanding across Europe.

To learn more about our story and company culture, visit us at

Who You Are

Medical Director with a proven track record of scientific and/or clinical accomplishments in either an academic or industry setting. Reporting to the Senior Vice President of Clinical Development, this role will have primary responsibility for all medical aspects pertaining to assigned clinical studies in treating multiple solid tumors, including breast cancer, non-small cell lung cancer, and colorectal cancer. Responsibilities include executing global Phase 1/1b studies. This role works collaboratively with multi-disciplinary teams responsible for designing, implementing, monitoring, analyzing, and reporting studies conducted within the BridegeBio Oncology Therapeutics portfolio to ensure the program meets the needs of patients and the business. This role will influence both internal and external audiences in a high-impact, prominent role as it actively contributes to the dynamic and innovative culture within the TheRas affiliate.  


  • Serve as clinical lead of a phase 1/1b study, including contributing to/overseeing study start-up, enrollment, study monitoring, data cleaning, and CSR writing
  • Lead internal project teams and partner with investigators and CROs to design and implement clinical studies, respectively
  • Write protocols, investigator brochures, and clinical study reports, and review clinical trial documents
  • Conduct investigator meetings and safety review committee meetings and lead site initiation visits with clinical trial investigators
  • Execute and deploy drug development strategic plans, develop contingency plans, provide technical and strategic advice, and meet milestones and budgets
  • Translate findings from research and nonclinical studies into clinical development opportunities
  • Interact with clinical investigators and thought leaders
  • Conduct clinical trials using ethical guidelines relevant to the pharmaceutical industry and ensure compliance with these external guidelines

No matter your role at BridgeBio, successful team members are:

  • Patient Champions, who put patients first and uphold strict ethical standards
  • Entrepreneurial Operators, who drive toward practical solutions and have an ownership mindset
  • Truth Seekers, who are detailed, rational, and humble problem solvers
  • Individuals Who Inspire Excellence in themselves and those around them
  • High-quality executors, who execute against goals and milestones with quality, precision, and speed

Education, Experience & Skills Requirements

  • Scientific and patient-focused MD (or equivalent) or MD/PhD with a deep commitment to understanding needs and improving the lives of patients and a passion for developing novel therapeutics
  • Demonstrated ability to collaborate successfully with multiple functions in a team environment
  • Demonstrated record of accomplishment in a compressed time frame; capable of prioritizing tasks and delivering on deadlines with high-performance standards and attention to detail
  • Motivated to work in a fast-paced, high accountability, small company environment; a “can do” and collegial professional who leads through influence and interpersonal skills
  • Intellectually curious with the courage to challenge and seek new ways to improve work
  • Strong written and oral communication skills, including presentation skills
  • Ability to analyze and interpret data and develop written reports and presentations of those data
  • Solid critical, strategic, and analytical thinking skills
  • Experience in all aspects of protocol conduct, both early and late phases, including protocol writing, start-up, study execution, analysis, and reporting
  • Minimum Education requirement
  • Travel (US and ex-US) required to scientific conferences and study sites as needed

What We Offer

  • Patient Days, where we are fortunate to hear directly from individuals living with the conditions we are seeking to impact throughout the year and learn how we can improve our efforts
  • A culture inspired by our values: put patients first, think independently, be radically transparent, every minute counts, and let the science speak
  • An unyielding commitment to always putting patients first. Learn more about how we do this here
  • A de-centralized model that enables our program teams to focus on advancing science and helping patients. Our affiliate structure is designed to eliminate bureaucracy and put decision-making power in the hands of those closest to the science
  • A place where you own the vision – both for your program and your own career path
  • A collaborative, fast-paced, data-driven environment where we inspire ourselves and each other to always perform at the top of our game
  • Access to learning and development resources to help you get in the best professional shape of your life
  • Robust and market-competitive compensation & benefits package (Base, Performance Bonus, Equity, health, welfare & retirement programs)
  • Flexible PTO
  • Rapid career advancement for strong performers
  • Potential ability to work on multiple BridgeBio Pharma programs across multiple therapeutic areas over time 
  • Partnerships with leading institutions
  • Commitment to Diversity, Equity & Inclusion
At BridgeBio, we strive to provide a market-competitive total rewards package, including base pay, an annual performance bonus, company equity, and generous health benefits. Below is the anticipated salary range for candidates for this role who will work in California. The final salary offered to a successful candidate will depend on several factors that may include but are not limited to the type and length of experience within the job, type, and length of experience within the industry, educational background, location of residence and performance during the interview process. BridgeBio is a multi-state employer, and this salary range may not reflect positions based in other states.
$260,000$315,000 USD


Medical Director

BridgeBio Oncology San Francisco, CA/Hybrid Clinical Development

Apply Now