BridgeBio finds, develops, and delivers breakthrough medicines for genetic diseases. The company bridges remarkable advancements in genetic science with the entrepreneurial engine required to rapidly create lifesaving medicines for patients with unmet needs. Founded in 2015 by a team of industry veterans, the company has built a portfolio of 20 transformative drugs ranging from pre-clinical to late-stage development in multiple therapeutic areas, including genetic dermatology, oncology, cardiology, neurology, endocrinology, renal disease, and ophthalmology. The company’s focus on scientific excellence and rapid execution aims to translate today’s discoveries into tomorrow’s medicines. We have offices in San Francisco, Palo Alto, Boston, New York, and Raleigh with small satellites in other parts of the country.
To learn more, visit us at https://bridgebio.com
San Francisco, CA
Who You Are
We are seeking an exceptional analyst to evaluate the progress of our drug pipeline and offer strategic guidance on organizational efficiency within the unique BridgeBio structure.
The position will work within Science Operations, a BridgeBio central team focused on institutionalizing rigorous standards and practices across affiliate companies. This position will be responsible for creating bespoke internal benchmarks to track the progress of preclinical, clinical, and commercial development. These include analyses of historical and projected timelines and costs within BridgeBio and the broader industry. Furthermore, this position will provide granular analytics of current clinical activities to provide real-time guidance on operational enrollment and retention strategies. From this information, this position will create key metrics of success that allow the organization to monitor efficiency and maximize ROI within development activities. This position reports to the Head of Science Operations under the Chief Executive Officer of BridgeBio.
This position is highly interdisciplinary and will collaborate with multiple teams across the company. It will work with Portfolio Intelligence to refine forecasting projections and Program Management to quantify and support BridgeBio leadership expectations. Additionally, this position will collaborate with FP&A to provide granular analyses of budgets and optimize future resource allocations within affiliates. This will include aggregating CRO contracts to create benchmark costs for external functions and comparing to internal resourcing costs as possible.
Collectively, this position will be responsible for codifying and enforcing the “BridgeBio standard” of development expectations as empirically derived from the portfolio of rare disease affiliates within BridgeBio. By constructing unique, relevant internal benchmarks, this position will deepen the understanding of BridgeBio’s collective activity and facilitate precise decision making at scale. Over time, this position will enable BridgeBio to capture the value of its portfolio-based model by enabling future programs to learn from existing ones.
- Quantify expectations for drug development progress by time and cost
- Define and monitor organizational performance metrics for efficiency
- Identify opportunities to scale best practices and strategies to circumvent rate-limiting steps
- Design granular clinical analytics to track clinical trial progress
- Deploy insights from clinical analytics through operational tactics and monitor effectiveness
- Implement probabilistic analyses to statistically aggregate possible future scenarios
- Aggregate information on historical development timelines and costs
- Analyze internal and external cost breakdowns within affiliate programs through development
- Aggregate CRO budgets and analyze cost breakdowns
- Research literature benchmarks for overall clinical development costs and as much detailed breakdown information as available
Education, Experience & Skills Requirements
- Strong communication skills to both technical and general audiences
- Demonstrated leadership capabilities of defining high-level strategic objectives and implementation plans
- Experience with financial analysis of drug development programs
- Experience with clinical development and clinical operations functions
- Understanding of key stakeholder perspectives throughout stages of development
- Systems-thinker comfortable with designing mechanistic, first-principles analyses
- Familiarity with statistical analysis methods including Monte Carlo simulations
- Background in engineering or economics
What We Offer
- Patient Days, where we are fortunate enough to learn more about the lives we are looking to impact and a real exchange of ideas as to how we can improve our efforts
- A culture inspired by our values: put patients first; think independently, be radically transparent; every minute counts, and let the science speak
- Learning and development training to help employees be the best version of themselves
- Collaborative business environment
- Excellent compensation package (Base, Performance Bonus, Stock, RSU programs)
- Excellent benefits package
- Flexible PTO
- With office locations in San Francisco, Boston, New York, and Raleigh, there are ample cross-collaboration opportunities with other BridgeBio Pharma programs
- A fast-paced, data-driven, work environment with world-class R&D minds and capabilities
- Work with the most productive groups of R&D operators in the industry
- Partnerships with leading institutions
- A platform for meaningful scientific contributions to shine
- Commitment to Diversity & Inclusion – with initiatives like Women at Bridge, we are committed to fostering an inclusive environment where every person feels respected for who they are, empowered to contribute, inspired to lead, and supported in their efforts to do so